Aldurazyme^® (laronidase)

Bibliographical Information:

Drug Name	Generic Name	Studied Indications or Disease	Approved U.S. Drug Label
Aldurazyme®	laronidase	mucopolysaccharidosis I (MPS I)	Prescribing Info

Protocol BIO 7500-001

Kakkis ED, Muenzer J, Tiller G, Waber L, Belmont J, Passage M, et al. Enzyme-replacement therapy in mucopolysaccharidosis I. N Engl J Med 2001;344(3):182-88.

Protocol ALID-003-99

Wraith J, Clarke L, Beck M, Kolodny E, Pastores G, Muenzer J, et al. Enzyme replacement therapy for mucopolysaccharidosis I: a randomized, double-blinded, placebo-controlled, multinational study of recombinant human α-L-iduronidase (lardonidase). J Pediatr 2004;144:581-8.