Thymoglobulin^® (anti-thymocyte globulin (rabbit))

Bibliographical Information:

Drug Name	Generic Name	Studied Indications or Disease	Approved U.S. Drug Label
Thymoglobulin®	anti-thymocyte globulin (rabbit)	Treatment of acute renal graft rejection in conjunction with concomitant immunosuppression	Prescribing Info

Protocol SANG-96-3-K-THY-I

Brennan DC, Flavin K, Lowell, JA et al. A randomized, double-blinded comparison of Thymoglobulin versus Atgam for induction immunosuppressive therapy in adult renal transplant recipients. Transplantation 1999;67(7):1011-1018.

Brennan DC, Flavin K, Lowell, JA et al. Leukocyte response to thymoglobulin or atgam for induction immunosuppression in a randomized, double-blind clinical trial in renal transplant recipients. Transplant Proc 1999;(3B Suppl):16S-18S.

Hardinger KL, Schnitzler MA, Miller B, et al. Five-year follow up of Thymoglobulin versus Atgam in adult renal transplantation. Transplantation 2004;78(1):136-141.

Protocol SANG-93-3-K-THY-R

Gaber AO, First MR, Tesi RJ, et al. Results of the double-blind, randomized, multicenter, phase III clinical trial of Thymoglobulin versus Atgam in the treatment of acute graft rejection episodes after renal transplantation. Transplantation 1998;66(1):29-37.

Schnitzler MA, Woodward RS, Lowell JA, et al. Economics of the antithymocyte globulins Thymoglobulin® and Atgam® in the treatment of acute renal transplant rejection. Pharmacoeconomics 2000;17(3):287-293.

Protocol SMC-101-1002

Brophy PD, Thomas SE, McBryde KD, Bunchman TE. Comparison of polyclonal induction agents in pediatric renal transplantation. Pediatr Transplantation 2001;5:174-178.

Protocols SMC-101-1007, SMC-101-1008, SMC-101-1009

Marvin MR, Droogan C, Sawinski D, Cohen DJ, Hardy MA. Administration of rabbit antithymocyte globulin (Thymoglobulin) in ambulatory renal-transplant patients. Transplantation 2003;75:488-489.

Protocol SMC-534-1003

Agha IA, Rueda J, Alvarez A, et al. Short course induction immunosuppression with Thymoglobulin for renal transplant recipients. Transplantation 2002;73(3):473-475.